課程資訊
課程名稱
藥物傳輸系統
Drug Delivery Systems 
開課學期
107-1 
授課對象
工學院  醫學工程學研究所  
授課教師
黃義侑 
課號
DBME7014 
課程識別碼
528 M0300 
班次
 
學分
3.0 
全/半年
半年 
必/選修
選修 
上課時間
星期四2,3,4(9:10~12:10) 
上課地點
 
備註
本課程中文授課,使用英文教科書。教室:基醫505
總人數上限:30人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1071DBME7014_ 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
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課程概述

一、課程簡介:
To provide the students with a broad spectrum of scientific information in a concise, systematic manner but with new vision and wider scope in drug delivery systems. Lectures include:
1. Concepts and System Design forthe Rate-Controlled Drug Delivery
2. Mathematical Modeling of Controlled Drug Delivery
3. Oral Drug Delivery and Delivery System
4. Mucosal Drug Delivery: Potential Routes for Noninvasive Systemic
Administration (Rectal & Oral musosa DDS)
5. Nasal/ Pulmonary Drug Delivery and Delivery System
6. Transdermal Drug Delivery and Delivery System
7. Ocular Drug Delivery and Delivery System
8. Polymers for Drug delivery, EVA, Silicone...
and Natural Biodegradable Polymer in Drug Delivery System
9. Synthetic Biodegradable Polymer in Drug Delivery System
10. Compartmental Models and Their Application
11. Drug Targeting
12. Liposome Drug Delivery
13. Study Report

二、先修課程:無
 

課程目標
To provide the students with a broad spectrum of scientific information in a concise, systematic manner but with new vision and wider scope in drug delivery systems.  
課程要求
無 
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
1. A.M. Hillery, A.W. Lloyd, J. Swarbrick “Drug delivery and Targeting for Pharmacists and Pharmaceutical Scientists ” Taylor & Francis, 2001
 
參考書目
1. A.M. Hillery, A.W. Lloyd, J. Swarbrick “Drug delivery and Targeting for
Pharmacists and Pharmaceutical Scientists ” Taylor & Francis, 2001
2. R.A. Bader, D.A. Putnam “Engineering Polymer Systems for Improved Drug Delivery”
Wiley 2014
3. J.Siepmann, R.A. Siegel, M.J. Rathbone “Fundamentals and Applications of
Controlled Release Drug Delivery” 2012 Springer
4. Polymers and Nanomaterials for Gene Therapy, Edited by:Ravin Narain 2016
 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
上課成績 
20% 
 
2. 
期中考試 
25% 
 
3. 
期末考試 
30% 
 
4. 
上台報告及書面報告 
25% 
 
 
課程進度
週次
日期
單元主題
第1週
9/13  Drug Delivery System-Introduction (I)
(核心能力:1,3,6) 
第2週
9/20  Drug Delivery System-Introduction (II)
(核心能力:2,4,7) 
第3週
9/27  DDS Mechanisms
(核心能力:1,2,4,6) 
第4週
10/04  DDS Mechanisms II
(核心能力:3,5,7) 
第5週
10/11  Polymer-drug conjugates
(核心能力:2,4,5) 
第6週
10/18  PEGylation of drug
(核心能力:1,2,6) 
第7週
10/25  Hydrogels for Drug delivery
(核心能力:2,3,5) 
第8週
11/01  Hydrophobic and biodegradable materials for Drug delivery
(核心能力:1,6,7) 
第9週
11/08  Mid-Term Quiz
(核心能力:1,4,7) 
第10週
11/15  校慶 停課一次
 
第11週
11/22  Nanoparticles for drug delivery system 
第12週
11/29  Liposomal drug delivery systems 
第18週
2019/01/10  期末考